MTHFD2 antibody (clone 4G7-2G3), anti-human
€435.00
In stock
SKU
AC-AT2928a
Catalog Number: AC-AT2928a
Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IHC
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Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IHC
Request Information AC-AT2928a">Request Information
Background:
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
Other Names:
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, NAD-dependent methylenetetrahydrofolate dehydrogenase, Methenyltetrahydrofolate cyclohydrolase, MTHFD2, NMDMC
Antigen Type:
Recombinant Protein
Gene Name: MTHFD2
Gene ID: 10797
NCBI Accession: NP_006627.2
Primary Accession: P13995
Other Accession: BC001548
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
Other Names:
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, NAD-dependent methylenetetrahydrofolate dehydrogenase, Methenyltetrahydrofolate cyclohydrolase, MTHFD2, NMDMC
Antigen Type:
Recombinant Protein
Gene Name: MTHFD2
Gene ID: 10797
NCBI Accession: NP_006627.2
Primary Accession: P13995
Other Accession: BC001548
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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