MTHFS Polyclonal Antibody

Background:
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5, 10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
10-methenyl-tetrahydrofolate synthetase, 5 10 methenyl tetrahydrofolate synthetase, 5, 5 formyltetrahydrofolate cyclo ligase, 5, 10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase), 5-formyltetrahydrofolate cyclo-ligase, FLJ30410, HsT19268, Methenyl THF synthetase, Methenyl-THF synthetase, MTHFS, MTHFS

Immunogen: Fusion protein of human MTHFS

Swissprot: P49914
Gene Accession: BC019921

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.68 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.