MTNR1A Polyclonal Antibody

Background:
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Research Area: Cancer, Metabolism, Neuroscience

Synonyms:
Mel 1A R, MEL-1A-R, Mel1a melatonin receptor, Mel1a receptor, Melatonin receptor 1A, Melatonin receptor type 1A, MelR, MR, MT 1, MT1, MTNR 1A, MTNR1A, MTR1A

Immunogen: Synthetic peptide of human MTNR1A

Swissprot: P48039
Gene Accession: NP_005949

Calculated MW: 39 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1 mg/mL
Dilution: WB 1:1000-1:3000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-13186/sc-13179/sc-30017/sc-13180