MTOR (phospho-S2448) polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Synonyms: FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS

Cellular Location: Cytoplasm Cytoplasmic side Endoplasmic reticulum membrane Golgi apparatus membrane Lysosome Mitochondrion outer membrane Nucleus PML body Peripheral membrane protein

Immunogen:
A phospho specific peptide corresponding to residues surrounding serine 2448 of human mTOR/FRAP

Gene Symbol: Phospho-MTOR-S2448

Gene ID: 2475

Swiss prot: P42345

Calculated MW: 289kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.