mTOR Polyclonal Antibody

Background:
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Research Area: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism

Synonyms:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1, SKS, mTOR, MTOR

Immunogen: A synthetic peptide of human mTOR (NP_004949.1).

Swissprot: P42345
Gene ID: 2475

Calculated MW: 288 kDa
Observed MW: 260 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.