mtTFA polyclonal, anti-human

Background:
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M.

Alternative Name:
mtTFA, MtTF1, TCF-6, TFAM, TCF6, TCF6L2, anscription factor 6-like 1, Mitochondrial transcription factor 1, mitochondrial transcription factor A, MtTF1, mtTFA, TCF 6, TCF-6, TCF6, TCF6L1, TCF6L2, TCF6L3, TFAM, TFAM, Transcription factor 6, Transcription factor 6 like 2 (mitochondrial transcription factor), Transcription factor 6 like 2, Transcription factor 6-like 2, transcription factor 6-like 3, Transcription factor A, mitochondrial, Transcription factor A, mitochondrial, Transcription factor A, mitochondrial precursor,

Application Dilution:
WB:1:200-1:500
ICC/IF:1:50-1:200
IHC:1:50-1:200
IP:1:10-1:50

Specificity: mtTFA polyclonal antibody detects endogenous levels of mtTFA protein.

Immunogen:
Recombinant protein

Swiss-Prot: Q00059(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.