MTTP polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6672
Background:
Microsomal triglyceride transfer protein (MTP), catalyzes the transport of cholesteryl ester, triglyceride and phospholipid between phospholipid surfaces. MTP is a heterodimer consisting of MTP and PDI (protein disulfide isomerase). It is required for the secretion of plasma lipoproteins containing apolipoprotein b. It is negatively regulation by insulin and positively regulated by cholesterol. MTP, which localizes to the endoplasmic reticulum (ER), is expressed primarily in small intestine and liver, kidney, testis and ovary. It is not expressed in epithelial cells. Defects in the MTP gene can cause abetalipoproteinemia (ABL) which is an autosomal recessive lipoprotein metabolism disorder.
Alternative Name:
ABL, Microsomal triglyceride transfer protein, Microsomal triglyceride transfer protein large subunit, MTP, MTTP,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: MTTP polyclonal antibody detects endogenous levels of MTTP protein.
Immunogen:
Recombinant full length Human MTTP.
MW: ~ 99 kDa
Swis Prot.: P55157
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Microsomal triglyceride transfer protein (MTP), catalyzes the transport of cholesteryl ester, triglyceride and phospholipid between phospholipid surfaces. MTP is a heterodimer consisting of MTP and PDI (protein disulfide isomerase). It is required for the secretion of plasma lipoproteins containing apolipoprotein b. It is negatively regulation by insulin and positively regulated by cholesterol. MTP, which localizes to the endoplasmic reticulum (ER), is expressed primarily in small intestine and liver, kidney, testis and ovary. It is not expressed in epithelial cells. Defects in the MTP gene can cause abetalipoproteinemia (ABL) which is an autosomal recessive lipoprotein metabolism disorder.
Alternative Name:
ABL, Microsomal triglyceride transfer protein, Microsomal triglyceride transfer protein large subunit, MTP, MTTP,
Application Dilution: WB: 1:500~1:2000, IHC/IF: 1:50~1:200
Specificity: MTTP polyclonal antibody detects endogenous levels of MTTP protein.
Immunogen:
Recombinant full length Human MTTP.
MW: ~ 99 kDa
Swis Prot.: P55157
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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