MUC1/EMA Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13623b
Background:
This gene is a member of the mucin family and encodes amembrane bound, glycosylated phosphoprotein. The protein isanchored to the apical surface of many epithelia by a transmembranedomain, with the degree of glycosylation varying with cell type. Italso includes a 20 aa variable number tandem repeat (VNTR) domain,with the number of repeats varying from 20 to 120 in differentindividuals. The protein serves a protective function by binding topathogens and also functions in a cell signaling capacity.Overexpression, aberrant intracellular localization, and changes inglycosylation of this protein have been associated with carcinomas.Multiple alternatively spliced transcript variants that encodedifferent isoforms of this gene have been reported, but thefull-length nature of only some has been determined. [provided byRefSeq].
Other Names:
Mucin-1, MUC-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, CA 15-3, Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive urinary mucin, PUM, Polymorphic epithelial mucin, PEM, Tumor-associated epithelial membrane antigen, EMA, Tumor-associated mucin, CD227, Mucin-1 subunit alpha, MUC1-NT, MUC1-alpha, Mucin-1 subunit beta, MUC1-beta, MUC1-CT, MUC1, PUM
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13623b was selected from the C-term region of MUC1/EMA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MUC1
Gene ID: 4582
Primary Accession: P15941
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is a member of the mucin family and encodes amembrane bound, glycosylated phosphoprotein. The protein isanchored to the apical surface of many epithelia by a transmembranedomain, with the degree of glycosylation varying with cell type. Italso includes a 20 aa variable number tandem repeat (VNTR) domain,with the number of repeats varying from 20 to 120 in differentindividuals. The protein serves a protective function by binding topathogens and also functions in a cell signaling capacity.Overexpression, aberrant intracellular localization, and changes inglycosylation of this protein have been associated with carcinomas.Multiple alternatively spliced transcript variants that encodedifferent isoforms of this gene have been reported, but thefull-length nature of only some has been determined. [provided byRefSeq].
Other Names:
Mucin-1, MUC-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, CA 15-3, Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive urinary mucin, PUM, Polymorphic epithelial mucin, PEM, Tumor-associated epithelial membrane antigen, EMA, Tumor-associated mucin, CD227, Mucin-1 subunit alpha, MUC1-NT, MUC1-alpha, Mucin-1 subunit beta, MUC1-beta, MUC1-CT, MUC1, PUM
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13623b was selected from the C-term region of MUC1/EMA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MUC1
Gene ID: 4582
Primary Accession: P15941
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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