MUC1-T1224 polyclonal, anti-human

MUC1-T1224 polyclonal, anti-human

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In stock
SKU
AC-AP10097a
Catalog Number: AC-AP10097a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16593
Applications: WB
Datasheet

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Background:
This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq].

Other Names:
Mucin-1, MUC-1, Breast carcinoma-associated antigen DF3, Cancer antigen 15-3, CA 15-3, Carcinoma-associated mucin, Episialin, H23AG, Krebs von den Lungen-6, KL-6, PEMT, Peanut-reactive urinary mucin, PUM, Polymorphic epithelial mucin, PEM, Tumor-associated epithelial membrane antigen, EMA, Tumor-associated mucin, CD227, Mucin-1 subunit alpha, MUC1-NT, MUC1-alpha, Mucin-1 subunit beta, MUC1-beta, MUC1-CT, MUC1, PUM

Target/Specificity:
This MUC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1202-1231 amino acids from human MUC1.

Antigen Region:
1202-1231

Antigen Type: Synthetic Peptide

Gene Name: MUC1
Gene ID: 4582
Primary Accession: P15941
NCBI Accession: NP_001018016.1;NP_001018017.1;NP_001037855.1;NP_001037856.1;NP_001037857.1;NP_001037858.1;NP_001191214.1;NP_001191215.1;NP_001191216.1;NP_001191217.1;NP_001191218.1;NP_001191219.1;NP_001191220.1;NP_00
Other Accession: NP_001037856.1;NP_001037858.1;NP_002447.4;NP_001037855.1;NP_001018016.1;NP_001037857.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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