MUC2 (clone EBS-T-233), anti-human

Source:
A BALB/c mouse was immunized with synthetic human MUC2 peptide (VNTR region).
Fusion partner: NS-1

Specifications:
EBS-T-233 reacts with GTQTP in the VNTR domain of human MUC2 (520 kDa). MUC2 is specifically expressed in goblet cells of the small intestine and colon and about 65% of colonic carcinomas and about 40% of gastric carcinomas are positive. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

Species reactivity:
Positive: human.

Applications:
Immunocytochemistry on frozen and paraffin sections. Immunofluorescence tests and Western blot.
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Paraffin sections: Tris/EDTA
Western blot: +

Positive control: LS174T cells (flow cytometry, Western blot), small intestine.

References:
- Xing, P.X. et al. J. Natl. Cancer Inst. 84, 699-703 (1992).