MUC20 Polyclonal Antibody

Background:
This gene encodes a member of the mucin protein family. Mucins are higHuman, Mouseolecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in most individuals. The allele represented in the human reference assembly contains 12 copies. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Signal Transduction

Synonyms:
MUC 20, MUC-20, Muc20, MUC20, Mucin 20, Mucin 20, cell surface associated, Mucin-20, Transmembrane mucin MUC20S

Immunogen: Recombinant protein of human MUC20

Swissprot: Q8N307
Gene Accession: BC029267

Calculated MW: 72 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.