MUC5AC (Mucin 5AC / Gastric Mucin) (clone SPM297 ), anti-human, mouse, rat, rabbit, primate, pig, chicken, cat
€0.00
In stock
SKU
AC-AH10610
Catalog Number: AC-AH10610
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM297
Applications: IHC-P, IF, FC
Datasheet
Request Information
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM297
Applications: IHC-P, IF, FC
Datasheet
Request Information
Background:
This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
Other Names:
Mucin-5AC, MUC-5AC, Gastric mucin, Lewis B blood group antigen, LeB, Major airway glycoprotein, Mucin-5 subtype AC, tracheobronchial, Tracheobronchial mucin, TBM, MUC5AC, MUC5
Gene Name: MUC5AC {ECO:0000303|PubMed:11535137, ECO:0000312|HGNC:HGNC:7515}
Gene ID: 4586
Primary Accession: P98088
Other Accession: 4586, 534332
This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
Other Names:
Mucin-5AC, MUC-5AC, Gastric mucin, Lewis B blood group antigen, LeB, Major airway glycoprotein, Mucin-5 subtype AC, tracheobronchial, Tracheobronchial mucin, TBM, MUC5AC, MUC5
Gene Name: MUC5AC {ECO:0000303|PubMed:11535137, ECO:0000312|HGNC:HGNC:7515}
Gene ID: 4586
Primary Accession: P98088
Other Accession: 4586, 534332
| Is Featured? | No |
|---|
Write Your Own Review