MUC5AC Polyclonal Antibody

Background:
Mucin-5ACis aproteinthat in humans is encoded by theMUC5ACgene. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD). Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.

Research Area: Cancer, Immunology, Signal Transduction

Synonyms:
Apomucin, Apomucin Major Airway Glycoprotein, Gastric mucin, LeB, Lewis B blood group antigen, Major Airway Glycoprotein, MUC 5, MUC5, MUC5AC, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5 subtypes A and C tracheobronchial/gastric, Mucin 5, tracheobronchial/gastric, Mucin 5AC, Mucin 5AC oligomeric mucus/gel forming, Mucin 5AC, oligomeric mucus/gel forming pseudogene, Mucin, TBM, Tracheobronchial Mucin (TBM), Tracheobronchial mucin

Immunogen: Synthetic peptide of human MUC5AC

Swissprot: P98088
Gene Accession: XP_003119529

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-16910/sc-71620/sc-20118