MUC5AC Polyclonal Antibody

Background:
Mucin-5ACis aproteinthat in humans is encoded by theMUC5ACgene. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD). Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.

Research Area: Cancer, Immunology, Signal Transduction

Synonyms:
Apomucin, Apomucin Major Airway Glycoprotein, Gastric mucin, LeB, Lewis B blood group antigen, Major Airway Glycoprotein, MUC 5, MUC5, MUC5AC, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5 subtypes A and C tracheobronchial/gastric, Mucin 5, tracheobronchial/gastric, Mucin 5AC, Mucin 5AC oligomeric mucus/gel forming, Mucin 5AC, oligomeric mucus/gel forming pseudogene, Mucin, TBM, Tracheobronchial Mucin (TBM), Tracheobronchial mucin

Immunogen: Recombinant Human Mucin-5AC protein

Swissprot: P98088

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 1 mg/mL
Dilution: IHC 1:100-1:400

Storage:
Store at -20°C. Avoid freeze / thaw cycles.