MUC5B Polyclonal Antibody

Background:
This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.

Research Area: Cancer, Cell Biology, Signal Transduction

Synonyms:
2300002I04Rik, A130042M24, AV085033, Cervical mucin, Cervical mucin MUC5B, High molecular weight salivary mucin MG1, MG1, MUC-5B, MUC5, MUC5B, MUC5B, MUC9, Mucin 5 subtype B, tracheobronchial, Mucin 5B, Mucin 5B oligomeric mucus/gel forming, Mucin-5 subtype B, Mucin-5B, Sublingual gland mucin, tracheobronchial

Immunogen: Synthetic peptide of human MUC5B

Swissprot: Q9HC84
Gene Accession: NP_002449

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-16911/sc-23025/sc-23024/sc-20119

Citation(s):
https://pubmed.ncbi.nlm.nih.gov/31877414/