MUC6 Polyclonal Antibody

Background:
The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis.

Research Area: Cancer, Signal Transduction

Synonyms:
Gastric mucin 6, Gastric mucin-6, MUC 6, MUC-6, Muc6, MUC6 Fragment, MUC6 mucin, MUC6 mucin Fragment, MUC6, Mucin 6, Mucin 6 gastric, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6 Fragment

Immunogen: Synthetic peptide of human MUC6

Swissprot: Q6W4X9
Gene Accession: NP_005952

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-16914/sc-16915