Mucin 13 rabbit polyclonal, anti-human, mouse, rat

Backgroud: Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008],function:Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.,PTM:Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homo-oligomerization into dimers is dependent on intrachain disulfide bonds.,PTM:Highly N-glycosylated.,similarity:Contains 1 SEA domain.,similarity:Contains 3 EGF-like domains.,subcellular location:Also exists as a soluble form.,subunit:Homodimer of beta subunits.,tissue specificity:Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach.,

Synonyms: MUC13, DRCC1, RECC, Mucin-13, MUC-13, Down-regulated in colon cancer 1

Gene Name: MUC13

Gene ID: 56667

SwissProt ID: Q9H3R2

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.