Mucin 5AC polyclonal, anti-human

Quantity: 100 µg

Background:
Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. MUC5AC is also a direct and critical mediator of resistance during intestinal nematode infection.

Description:
Rabbit IgG polyclonal antibody for Mucin-5AC (MUC5AC) detection. Tested with WB, IHC-P in Human.

Synonyms:
Apomucin antibody, Gastric mucin antibody, Major Airway Glycoprotein antibody, MUC 5 antibody, MUC5 antibody, MUC5AC antibody, Mucin 5 subtype AC tracheobronchial antibody, Mucin 5 Subtypes A And C antibody, Mucin 5 subtypes A and C tracheobronchial/gastric antibody, Mucin 5AC oligomeric mucus/gel forming antibody, TBM antibody, Tracheobronchial Mucin antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Mucin 5AC(552-567aa TMQLFMQLAPKLRGQT).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.