MUL1 polyclonal (C-term), anti-human

MUL1 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP12811b
Catalog Number: AC-AP12811b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32336
Applications: WB
Datasheet

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Background:
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Other Names:
Mitochondrial ubiquitin ligase activator of NFKB 1, 632-, E3 SUMO-protein ligase MUL1, E3 ubiquitin-protein ligase MUL1, Growth inhibition and death E3 ligase, Mitochondrial-anchored protein ligase, MAPL, Putative NF-kappa-B-activating protein 266, RING finger protein 218, MUL1, C1orf166, GIDE, MAPL, MULAN, RNF218

Target/Specificity:
This MUL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human MUL1.

Antigen Region:
272-301

Antigen Type: Synthetic Peptide

Gene Name: MUL1
Gene ID: 79594
Primary Accession: Q969V5
NCBI Accession: NP_078820.2
Other Accession: Q4R7G8; NP_078820.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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