Munc-18 (Ser515) polyclonal, anti-human, mouse, rat, bovine, dog, chicken, xenopus, monkey
€536.00
In stock
SKU
252559
Catalog Nr.: 252559
Size: 0.1 ml
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
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Size: 0.1 ml
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
Request Information
Protein Family: SNAREs, Chaperones and Folding Catalysts
Pathway and Disease: Membrane Transport, Nervous and Sensory Systems
Description:
Syntaxin-binding protein 2 (Munc-18) is involved in intracellular vesicle trafficking and vesicle fusion with membranes. Munc-18 contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Munc-18 regulates cytotoxic granule exocytosis in natural killer (NK) cells. The function of Munc-18 is regulated by PKC phosphorylation of Ser515.
Alternate Names: Syntaxin-binding protein 2, Protein unc-18 homolog 2, Munc18-2, Unc18-2, Protein unc-18 homolog B, Unc-18B
Application Notes: E: 1:1,000; WB: 1:1,000; IHC: 1:400
Accession No.: Q62753
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser515 of rat munc-18.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Membrane Transport, Nervous and Sensory Systems
Description:
Syntaxin-binding protein 2 (Munc-18) is involved in intracellular vesicle trafficking and vesicle fusion with membranes. Munc-18 contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Munc-18 regulates cytotoxic granule exocytosis in natural killer (NK) cells. The function of Munc-18 is regulated by PKC phosphorylation of Ser515.
Alternate Names: Syntaxin-binding protein 2, Protein unc-18 homolog 2, Munc18-2, Unc18-2, Protein unc-18 homolog B, Unc-18B
Application Notes: E: 1:1,000; WB: 1:1,000; IHC: 1:400
Accession No.: Q62753
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser515 of rat munc-18.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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