Munc13-4 / UNC13D (C terminus) polyclonal, anti-human

Background:
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.

Other Names:
Protein unc-13 homolog D, Munc13-4, UNC13D

Antigen Types:
Synthetic Peptide

Gene Name:
UNC13D
Gene ID:
201294
Primary Accession: Q70J99
Other Accession: NP_954712;201294;