Musashi-1 (clone ), anti-human, mouse, rat
€388.00
In stock
SKU
MB0154
Background:
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5´-GUUAGUUAGUUAGUU-3´ and other sequences containing the pattern 5´-[GA]U1-3AGU-3´. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
Alternative Name:
RNA-binding protein Musashi homolog 1, Musashi-1, MSI1
Application Dilution: WB: 1:1000
Specificity: This antibody detects endogenous levels of Musashi-1 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human Musashi-1.
MW: Predicted band size: 39KDa , Observed band size: 39KDa
Swis Prot.: O43347
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5´-GUUAGUUAGUUAGUU-3´ and other sequences containing the pattern 5´-[GA]U1-3AGU-3´. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
Alternative Name:
RNA-binding protein Musashi homolog 1, Musashi-1, MSI1
Application Dilution: WB: 1:1000
Specificity: This antibody detects endogenous levels of Musashi-1 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human Musashi-1.
MW: Predicted band size: 39KDa , Observed band size: 39KDa
Swis Prot.: O43347
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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