muscarinic Acetylcholine Receptor 1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Muscarinic acetylcholine receptor M1, also known as cholinergic receptor, muscarinic 1, is a muscarinic receptor. This gene is mapped to 11q12.3. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract.

Description:
Rabbit IgG polyclonal antibody for Muscarinic acetylcholine receptor M1 (CHRM1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Cholinergic receptor muscarinic 1 antibody, CHRM 1 antibody, CHRM1 antibody, HM 1 antibody, HM1 antibody, M1 antibody, M1 muscarinic cholinergic receptor antibody, MGC30125 antibody, Muscarinic acetylcholine receptor M1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human muscarinic Acetylcholine Receptor 1(303-317aa KMPMVDPEAQAPTKQ), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.