Musculin polyclonal antibody, anti-human, mouse

Background:
Musculin encoded by MSC is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. Musculin also forms heterodimers with E2A proteins in vivo. Musculin is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. MSC is a downstream target of the B-cell receptor signal transduction pathway.

Research Area: Epigenetics and Nuclear Signaling

Synonyms: MSC, ABF1, BHLHA22, Musculin, Activated B-cell factor 1, ABF-1, Class A basic helix-loop-helix protein 22, bHLHa22

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year