MUSK polyclonal, anti-human, mouse
€0.00
In stock
SKU
AC-AP7664D
Catalog Number: AC-AP7664D
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14743
Applications: IF, FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB14743
Applications: IF, FC, WB
Datasheet
Request Information
Background:
MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
Other Names:
Muscle, skeletal receptor tyrosine-protein kinase, Muscle-specific tyrosine-protein kinase receptor, MuSK, Muscle-specific kinase receptor, MUSK
Target/Specificity:
This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: MUSK
Gene ID: 4593
Primary Accession: O15146
NCBI Accession: NP_001159752.1;NP_001159753.1;NP_005583.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
Other Names:
Muscle, skeletal receptor tyrosine-protein kinase, Muscle-specific tyrosine-protein kinase receptor, MuSK, Muscle-specific kinase receptor, MUSK
Target/Specificity:
This MUSK antibody is generated from rabbits immunized with human MUSK recombinant protein.
Antigen Type: Recombinant Protein
Gene Name: MUSK
Gene ID: 4593
Primary Accession: O15146
NCBI Accession: NP_001159752.1;NP_001159753.1;NP_005583.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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