MUTYH Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP9161c
Background:
MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.
Other Names:
A/G-specific adenine DNA glycosylase, 322-, MutY homolog, hMYH, MUTYH, MYH
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9161c was selected from the Center region of human MUTYH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MUTYH
Gene ID: 4595
Primary Accession: Q9UIF7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.
Other Names:
A/G-specific adenine DNA glycosylase, 322-, MutY homolog, hMYH, MUTYH, MYH
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9161c was selected from the Center region of human MUTYH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MUTYH
Gene ID: 4595
Primary Accession: Q9UIF7
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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