MUTYH polyclonal, anti-human

Background:
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Other Names:
A/G-specific adenine DNA glycosylase, 3.2.2.-, MutY homolog, hMYH, MUTYH, MYH

Antigen Types:
Synthetic Peptide

Gene Name:
MUTYH
Gene ID:
4595
Primary Accession: Q9UIF7
Other Accession: NP_001121897;4595;