MUTYH polyclonal, anti-human

Background:
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: MYH

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human MUTYH

Gene Symbol: MUTYH

Gene ID: 4595

Swiss prot: Q9UIF7

Calculated MW: 60kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:10-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.