MUTYH polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP9161c
Catalog Number: AC-AP9161c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17460
Applications: IF, FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17460
Applications: IF, FC, WB
Datasheet
Request Information
Background:
MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.
Other Names:
A/G-specific adenine DNA glycosylase, 322-, MutY homolog, hMYH, MUTYH, MYH
Target/Specificity:
This MUTYH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the Central region of human MUTYH.
Antigen Region:
341-367
Antigen Type: Synthetic Peptide
Gene Name: MUTYH
Gene ID: 4595
Primary Accession: Q9UIF7
NCBI Accession: NP_001041636.1;NP_001041637.1;NP_001041638.1;NP_001041639.1;NP_001121897.1;NP_036354.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.
Other Names:
A/G-specific adenine DNA glycosylase, 322-, MutY homolog, hMYH, MUTYH, MYH
Target/Specificity:
This MUTYH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the Central region of human MUTYH.
Antigen Region:
341-367
Antigen Type: Synthetic Peptide
Gene Name: MUTYH
Gene ID: 4595
Primary Accession: Q9UIF7
NCBI Accession: NP_001041636.1;NP_001041637.1;NP_001041638.1;NP_001041639.1;NP_001121897.1;NP_036354.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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