MVK Polyclonal Antibody

Background:
This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
FLJ96772, KIME, LH receptor mRNA binding protein, LRBP, Mevalonate kinase 1, Mevalonate kinase, Mevalonic aciduria, MK, mvk, MVLK, POROK3

Immunogen: Recombinant protein of human MVK

Swissprot: Q03426
Gene Accession: BC016140

Calculated MW: 42 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-27587/sc-27585