MVP antibody (clone 2H3-1A6), anti-human
€435.00
In stock
SKU
AC-AT2941a
Catalog Number: AC-AT2941a
Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, IHC, IF, E
Request Information AC-AT2941a">Request Information
Background:
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
Other Names:
Major vault protein, MVP, Lung resistance-related protein, MVP, LRP
Antigen Type:
Recombinant Protein
Gene Name: MVP
Gene ID: 9961
NCBI Accession: NP_005106.2;NP_059447.2
Primary Accession: Q14764
Other Accession: BC015623
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
Other Names:
Major vault protein, MVP, Lung resistance-related protein, MVP, LRP
Antigen Type:
Recombinant Protein
Gene Name: MVP
Gene ID: 9961
NCBI Accession: NP_005106.2;NP_059447.2
Primary Accession: Q14764
Other Accession: BC015623
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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