MVP monoclonal (N-term) (Ascites), anti-human
€470.00
In stock
SKU
AC-AM2146a
Catalog Number: AC-AM2146a
Size: 100 µl
Isotype: mouse IgG1
Clone Name: 599CT2.4.1
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgG1
Clone Name: 599CT2.4.1
Applications: WB
Datasheet
Request Information
Background:
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
Other Names:
Major vault protein, MVP, Lung resistance-related protein, MVP, LRP
Target/Specificity:
This MVP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human MVP.
Antigen Region:
12-39
Antigen Type: Synthetic Peptide
Gene Name: MVP
Gene ID: 9961
Primary Accession: Q14764
NCBI Accession: NP_005106.2;NP_059447.2
Other Accession: Q62667; Q9EQK5; Q3SYU9; NP_005106.2
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
Other Names:
Major vault protein, MVP, Lung resistance-related protein, MVP, LRP
Target/Specificity:
This MVP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of human MVP.
Antigen Region:
12-39
Antigen Type: Synthetic Peptide
Gene Name: MVP
Gene ID: 9961
Primary Accession: Q14764
NCBI Accession: NP_005106.2;NP_059447.2
Other Accession: Q62667; Q9EQK5; Q3SYU9; NP_005106.2
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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