MXI1 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP14974c
Background:
Expression of the c-myc gene, which produces an oncogenictranscription factor, is tightly regulated in normal cells but isfrequently deregulated in human cancers. The protein encoded bythis gene is a transcriptional repressor thought to negativelyregulate MYC function, and is therefore a potential tumorsuppressor. This protein inhibits the transcriptional activity ofMYC by competing for MAX, another basic helix-loop-helix proteinthat binds to MYC and is required for its function. Defects in thisgene are frequently found in patients with prostate tumors. Threealternatively spliced transcripts encoding different isoforms havebeen described. Additional alternatively spliced transcripts mayexist but the products of these transcripts have not been verifiedexperimentally.
Other Names:
Max-interacting protein 1, Max interactor 1, Class C basic helix-loop-helix protein 11, bHLHc11, MXI1, BHLHC11
Gene Name: MXI1
Gene ID: 4601
Primary Accession: P50539
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Expression of the c-myc gene, which produces an oncogenictranscription factor, is tightly regulated in normal cells but isfrequently deregulated in human cancers. The protein encoded bythis gene is a transcriptional repressor thought to negativelyregulate MYC function, and is therefore a potential tumorsuppressor. This protein inhibits the transcriptional activity ofMYC by competing for MAX, another basic helix-loop-helix proteinthat binds to MYC and is required for its function. Defects in thisgene are frequently found in patients with prostate tumors. Threealternatively spliced transcripts encoding different isoforms havebeen described. Additional alternatively spliced transcripts mayexist but the products of these transcripts have not been verifiedexperimentally.
Other Names:
Max-interacting protein 1, Max interactor 1, Class C basic helix-loop-helix protein 11, bHLHc11, MXI1, BHLHC11
Gene Name: MXI1
Gene ID: 4601
Primary Accession: P50539
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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