MYBPC3 polyclonal, anti-rat

Background:
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.

Synonyms: CMD1MM, CMH4, FHC, LVNC10, MYBP-C

Cellular Location: Cytoskeleton Cytosol

Immunogen:
Recombinant protein of human MYBPC3

Gene Symbol: MYBPC3

Gene ID: 4607

Swiss prot: Q14896

Calculated MW: 141kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.