MYC Antibody (C-term T400) Blocking Peptide
€363.00
In stock
SKU
AC-BP14477b
Background:
The protein encoded by this gene is a multifunctional,nuclear phosphoprotein that plays a role in cell cycle progression,apoptosis and cellular transformation. It functions as atranscription factor that regulates transcription of specifictarget genes. Mutations, overexpression, rearrangement andtranslocation of this gene have been associated with a variety ofhematopoietic tumors, leukemias and lymphomas, including Burkittlymphoma. There is evidence to show that alternative translationinitiations from an upstream, in-frame non-AUG (CUG) and adownstream AUG start site result in the production of two isoformswith distinct N-termini. The synthesis of non-AUG initiated proteinis suppressed in Burkitt's lymphomas, suggesting its importance inthe normal function of this gene.
Other Names:
Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39
Gene Name: MYC
Gene ID: 4609
Primary Accession: P01106
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a multifunctional,nuclear phosphoprotein that plays a role in cell cycle progression,apoptosis and cellular transformation. It functions as atranscription factor that regulates transcription of specifictarget genes. Mutations, overexpression, rearrangement andtranslocation of this gene have been associated with a variety ofhematopoietic tumors, leukemias and lymphomas, including Burkittlymphoma. There is evidence to show that alternative translationinitiations from an upstream, in-frame non-AUG (CUG) and adownstream AUG start site result in the production of two isoformswith distinct N-termini. The synthesis of non-AUG initiated proteinis suppressed in Burkitt's lymphomas, suggesting its importance inthe normal function of this gene.
Other Names:
Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39
Gene Name: MYC
Gene ID: 4609
Primary Accession: P01106
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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