MYCN polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70167
Background:
MYCN, also named as BHLHE37 and NMYC, is a transcription factor. It is primarily expressed in normal developing embryos and is thought to be critical in brain and other neural development. It is often amplified in human neuroblastomas. IR34A can suppress MYCN expression, it suggest MYCN has a role in cell growth. The expression of the MCYN is upregulated in a variety of human tumors, most requently neuroblastoma, where the level of expression appearts to increase as teh tumor progress.
Alternative Name:
NMYC, ODED, MODED, N-myc, MYCNOT, bHLHe37,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: MYCN polyclonal antibody detects endogenous levels of MYCN protein.
Immunogen:
Recombinant protein of human MYCN.
MW: ~ 65 kDa
Swis Prot.: P04198
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
MYCN, also named as BHLHE37 and NMYC, is a transcription factor. It is primarily expressed in normal developing embryos and is thought to be critical in brain and other neural development. It is often amplified in human neuroblastomas. IR34A can suppress MYCN expression, it suggest MYCN has a role in cell growth. The expression of the MCYN is upregulated in a variety of human tumors, most requently neuroblastoma, where the level of expression appearts to increase as teh tumor progress.
Alternative Name:
NMYC, ODED, MODED, N-myc, MYCNOT, bHLHe37,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: MYCN polyclonal antibody detects endogenous levels of MYCN protein.
Immunogen:
Recombinant protein of human MYCN.
MW: ~ 65 kDa
Swis Prot.: P04198
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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