MYD88, Biotinylated polyclonal, anti-human

Background:
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Other Names:
Myeloid differentiation primary response protein MyD88, MYD88

Antigen Types:
Synthetic Peptide

Gene Name:
MYD88 (HGNC:7562)
Gene ID:
4615
Primary Accession: Q99836
Other Accession: NP_002459;4615;17874 (mouse); 301059 (rat);