MyD88 polyclonal, anti-human

Background:
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription.

Synonyms: myeloid differential protein-88, Myeloid differentiation primary response gene, MYD 88, MYD88D, Myeloid differentiation marker 88, Myeloid differentiation primary response gene 88

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human MyD88

Gene Symbol: MyD88

Gene ID: 17874

Swiss prot: P22366

Calculated MW: 34kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.