MyD88 polyclonal, anti-human, mouse, rat

Protein Family: Receptors and Channels

Pathway and Disease: Immune System, Infectious Diseases, Cell Growth and Death

Description:
Myeloid differentiation primary response protein MyD88 (MyD88) is an adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. MyD88 acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. MyD88 increases IL-8 transcription and is also involved in IL-18-mediated signaling pathway.

Alternate Names: MyD88, Myeloid differentiation protein-88, Myelloid differentiation primary response protein MyD88

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500

Accession No.: Q99836

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of MyD88.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.