Myelin Basic Protein polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Myelin basic protein(MBP) is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the central nervous system and the peripheral nervous system, respectively. It is most abundant in hemopoietic system and contains seven exons distributed over 32-34 kb. MBP isolated from MS brain may differ in charge microheterogeneity which would affect antigenic determinants. MBP is mapped to chromosome 18q22-23. Failure in this gene expression would be correlated in the central white matter with extrapyramidal system degeneration signs. Moreover, it is a candidate autoantigen in the disease multiple sclerosis.

Description:
Rabbit IgG polyclonal antibody for Myelin basic protein (MBP) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
GDB antibody, Golli MBP antibody, Hemopoietic MBP antibody, HMBPR antibody, HUGO antibody, MBP antibody, MBP_HUMAN antibody, MGC99675 antibody, MLD antibody, Myelin A1 Protein antibody, Myelin basic protein antibody, Myelin Deficient antibody, Myelin Membrane Encephalitogenic Protein antibody, OTTHUMP00000163776 antibody, OTTHUMP00000174387 antibody, OTTHUMP00000174388 antibody, SHI antibody, Shiverer antibody, SP antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Myelin Basic Protein(182-197aa KLGGRDSRSGSPMARR), identical to the related rat and mouse sequences.A synthetic peptide corresponding to a sequence at the C-terminus of human Myelin Basic Protein(182-197aa KLGGRDSRSGSPMARR), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.