Myeloperoxidase polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Myeloperoxidase(MPO) is a mammalian phagocyte hemoprotein though to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function.

Description:
Rabbit IgG polyclonal antibody for Myeloperoxidase (MPO) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
84 kDa myeloperoxidase antibody, 89 kDa myeloperoxidase antibody, EC 1.11.1.7 antibody, EC1.11.2.2 antibody, MPO antibody, Myeloperoxidase heavy chain antibody, Myeloperoxidase light chain antibody, PERM_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Myeloperoxidase(714-728aa KNNIFMSNSYPRDFV), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence at the C-terminus of human Myeloperoxidase(714-728aa KNNIFMSNSYPRDFV), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.