Myeloperoxidase polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function. The standard product used in this kit is the product of gene recombination, consisting of 697(A49-S745) amino acids with the molecular mass of 80KDa.

Description:
Rabbit IgG polyclonal antibody for Myeloperoxidase (MPO) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
84 kDa myeloperoxidase antibody, 89 kDa myeloperoxidase antibody, EC 1.11.1.7 antibody, EC1.11.2.2 antibody, MPO antibody, Myeloperoxidase heavy chain antibody, Myeloperoxidase light chain antibody, PERM_HUMAN antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Myeloperoxidase recombinant protein (Position:S406-S745). Human Myeloperoxidase shares 90% amino acid (aa) sequence identity with mouse Myeloperoxidase.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.