MYH Polyclonal Antibody

Background:
mutY DNA glycosylase(MUTYH) Homo sapiens This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Alternative Names:
MUTYH, MYH, A/G-specific adenine DNA glycosylase, MutY homolog, hMYH

Immunogen: The antiserum was produced against synthesized peptide derived from human MUTYH. AA range:151-200

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 60

GeneID: MUTYH

Storage: -20°C/1 year

NOTE: For Research Use Only