MYH8 polyclonal, anti-human
€305.00
In stock
SKU
BS61311
Background:
Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures, and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer of two heavy chains (MHC) and four light chains (MLC) that interact with Actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. MYH3 (Myosin heavy chain 3), also known as muscle embryonic Myosin heavy chain or SMHCE, is a 1,940 amino acid that localizes to the thick filaments of myofibrils. While highly expressed in fetal skeletal muscle, MYH3 is barely detectable in adult skeletal muscle. Defects in the gene encoding MYH3, which maps to human chromosome 17p13.1, are the cause of distal arthrogryposis type 2B (DA2B).
Alternative Name:
Myosin-8, Myosin heavy chain 8, Myosin heavy chain, skeletal muscle, perinatal, MyHC-perinatal, MYH8
Application Dilution: WB: 1:500~1:1000
Specificity: MYH8 polyclonal antibody detects endogenous levels of MYH8 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human MYH8.
MW: ~ 223 kDa
Swis Prot.: P13535
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures, and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer of two heavy chains (MHC) and four light chains (MLC) that interact with Actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. MYH3 (Myosin heavy chain 3), also known as muscle embryonic Myosin heavy chain or SMHCE, is a 1,940 amino acid that localizes to the thick filaments of myofibrils. While highly expressed in fetal skeletal muscle, MYH3 is barely detectable in adult skeletal muscle. Defects in the gene encoding MYH3, which maps to human chromosome 17p13.1, are the cause of distal arthrogryposis type 2B (DA2B).
Alternative Name:
Myosin-8, Myosin heavy chain 8, Myosin heavy chain, skeletal muscle, perinatal, MyHC-perinatal, MYH8
Application Dilution: WB: 1:500~1:1000
Specificity: MYH8 polyclonal antibody detects endogenous levels of MYH8 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human MYH8.
MW: ~ 223 kDa
Swis Prot.: P13535
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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