MYL7 polyclonal, anti-human, mouse, rat

Background:
Encoded by the MYL7 gene, myosin regulatory light chain 7, also designated Myosin regulatory light chain 2, atrial isoform (MLC-2a), is part of a hexameric complex of two heavy chains and four light chains predominantly expressed in adult atrial muscle. Myosin regulatory light chain 7 binds calcium and has been shown to be a useful molecular marker for cardiac chamber specification. The co-expression of myosin regulatory light chain 7 and myosin light chain 2 (MLC2v) in the outflow tract and atrioventricular canal, together with the single expression in the atrial (MYL7) and ventricular (MYL2) myo-cardium, permits the delineation of their boundaries. At the amino acid level there is 95% homology between the human and mouse myosin regulatory light chain 7 sequences.

Alternative Name:
Myosin regulatory light chain 2, atrial isoform, MLC-2a, MLC2a, Myosin light chain 2a, Myosin regulatory light chain 7, MYL2A, MYLC2A

Application Dilution: WB: 1:500~1:1000

Specificity: MYL7 polyclonal antibody detects endogenous levels of MYL7 protein.

Immunogen:
Synthetic peptide, corresponding to amino acids 130-175 of Human MYL7.

MW: ~ 19 kDa

Swis Prot.: Q01449

Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.