MYL9 (phospho-S19) polyclonal, anti-human, mouse, rat
€328.00
In stock
SKU
BS4845
Background:
Myosin regulatory light chains, including MRCL3 (also known as MRLC3 or MLCB), MRLC2 (also known as MLC-B) and MYL9 (also known as LC20, MLC2, MRLC1 or MYRL2), regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the Actin-activated myosin ATPase activity, thereby regulating the contractile activity. Myosin light chain is also located in striated skeletal muscle, where its function remains undefined.
Alternative Name:
Myosin regulatory light polypeptide 9, 20 kDa myosin light chain, Short name=LC20, MLC-2C, Myosin RLC, Myosin regulatory light chain 2, smooth muscle isoform, Myosin regulatory light chain 9, Myosin regulatory light chain MRLC1, MLC2, MRLC1, MYRL2, Myosin regulatory light chain 12A, MLC-2B, Myosin RLC, Myosin regulatory light chain 2, nonsarcomeric, Myosin regulatory light chain MRLC3, MYL12A, MLCB, MRLC3, RLC
Application Dilution: WB: 1:500~1:1000
Specificity: p-MYL9 (S19) polyclonal antibody detects endogenous levels of MYL9 protein only when phosphorylated at Ser19. This antibody may detects endogenous levels of MYL12A protein only when phosphorylated at Ser18.
Immunogen:
Synthetic phosphopeptide derived from human MYL9 around the phosphorylation site of Serine 19.
MW: ~ 20 kDa
Swis Prot.: P24844/P19105
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Myosin regulatory light chains, including MRCL3 (also known as MRLC3 or MLCB), MRLC2 (also known as MLC-B) and MYL9 (also known as LC20, MLC2, MRLC1 or MYRL2), regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the Actin-activated myosin ATPase activity, thereby regulating the contractile activity. Myosin light chain is also located in striated skeletal muscle, where its function remains undefined.
Alternative Name:
Myosin regulatory light polypeptide 9, 20 kDa myosin light chain, Short name=LC20, MLC-2C, Myosin RLC, Myosin regulatory light chain 2, smooth muscle isoform, Myosin regulatory light chain 9, Myosin regulatory light chain MRLC1, MLC2, MRLC1, MYRL2, Myosin regulatory light chain 12A, MLC-2B, Myosin RLC, Myosin regulatory light chain 2, nonsarcomeric, Myosin regulatory light chain MRLC3, MYL12A, MLCB, MRLC3, RLC
Application Dilution: WB: 1:500~1:1000
Specificity: p-MYL9 (S19) polyclonal antibody detects endogenous levels of MYL9 protein only when phosphorylated at Ser19. This antibody may detects endogenous levels of MYL12A protein only when phosphorylated at Ser18.
Immunogen:
Synthetic phosphopeptide derived from human MYL9 around the phosphorylation site of Serine 19.
MW: ~ 20 kDa
Swis Prot.: P24844/P19105
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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