MYO1C Polyclonal Antibody

Background:
This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.

Research Area: Cancer, Signal Transduction

Synonyms:
MYO1C, MMI-beta, MMIb, NMI, myr2, myosin IC

Immunogen: Recombinant fusion protein of human MYO1C (NP_203693.3).

Swissprot: O00159
Gene ID: 4641

Calculated MW: 117 kDa/119 kDa/121 kDa
Observed MW: 122 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.