MYO3A Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP6371b
Background:
MYO3A belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. This protein plays an important role in hearing in humans. Three different recessive loss of function mutations have been shown to cause nonsyndromic progressive hearing loss.
Other Names:
Myosin-IIIa, MYO3A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6371b was selected from the C-term region of human MYO3A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MYO3A
Gene ID: 53904
Primary Accession: Q8NEV4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
MYO3A belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. This protein plays an important role in hearing in humans. Three different recessive loss of function mutations have been shown to cause nonsyndromic progressive hearing loss.
Other Names:
Myosin-IIIa, MYO3A
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6371b was selected from the C-term region of human MYO3A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: MYO3A
Gene ID: 53904
Primary Accession: Q8NEV4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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