MYO3A antibody (clone 8D12), anti-human
€435.00
In stock
SKU
AC-AT2958a
Catalog Number: AC-AT2958a
Size: 50 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
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Size: 50 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
Request Information AC-AT2958a">Request Information
Background:
The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea.
Other Names:
Myosin-IIIa, MYO3A
Antigen Type:
Recombinant Protein
Gene Name: MYO3A
Gene ID: 53904
NCBI Accession: NP_059129.3
Primary Accession: Q8NEV4
Other Accession: NM_017433
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene belongs to the myosin superfamily. Myosins are actin-dependent motor proteins and are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as this one, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. The protein encoded by this gene plays an important role in hearing in humans. Three different recessive, loss of function mutations in the encoded protein have been shown to cause nonsyndromic progressive hearing loss. Expression of this gene is highly restricted, with the strongest expression in retina and cochlea.
Other Names:
Myosin-IIIa, MYO3A
Antigen Type:
Recombinant Protein
Gene Name: MYO3A
Gene ID: 53904
NCBI Accession: NP_059129.3
Primary Accession: Q8NEV4
Other Accession: NM_017433
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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