MYO3B Antibody (N-term) Blocking Peptide

Background:
Similar to other class III myosins, MYO3B contains an N-terminal kinase domain, followed by motor, neck, and tail domains. The MYO3B gene generates a variety of splice variants that contain 1 or 2 calmodulin-binding (IQ) motifs in the neck domain and 1 of 3 domains in the tail domain. Northern blot analysis showed expression of a 7-kb MYO3B transcript in human retina, but not in an RPE cell line; two 6- and 7-kb MYO3B transcripts in kidney; and a 4-kb transcript in testis.

Other Names:
Myosin-IIIb, MYO3B

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7155a was selected from the N-term region of human MYO3B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: MYO3B

Gene ID: 140469
Primary Accession: Q8WXR4
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.